Search results for "Location systems"

showing 3 items of 3 documents

Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.

2019

Background & Aims Increased hepatocyte death contributes to the pathology of acute and chronic liver diseases. However, the role of hepatocyte pyroptosis and extracellular inflammasome release in liver disease is unknown. Methods We used primary mouse and human hepatocytes, hepatocyte-specific leucine 351 to proline Nlrp3KICreA mice, and GsdmdKO mice to investigate pyroptotic cell death in hepatocytes and its impact on liver inflammation and damage. Extracellular NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasomes were isolated from mutant NLRP3-YFP HEK cells and internalisation was studied in LX2 and primary human hepatic stellate cells. We also examined a cohort of 154…

0301 basic medicineLiver CirrhosisInflammasomesInterleukin-1betaArticle03 medical and health sciencesLiver diseaseMice0302 clinical medicineMice Inbred NODNon-alcoholic Fatty Liver DiseaseNLR Family Pyrin Domain-Containing 3 ProteinmedicineHepatic Stellate CellsPyroptosisAnimalsHumansLiver injuryHepatologyChemistryFatty liverCaspase 1PyroptosisInflammasomemedicine.disease3. Good healthCell biology030104 developmental biologymedicine.anatomical_structureHepatocyteHepatic stellate cellHepatocytesProtein Translocation Systems030211 gastroenterology & hepatologySteatohepatitisReactive Oxygen Speciesmedicine.drugJournal of hepatology
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Newtonian and relativistic location systems

2008

The theory of location systems involves the geometric and physical description of the protocols allowing the realization of coordinate systems. In this communication, the incidence of the space-time causal structure (Newtonian or relativistic) on the construction of location systems is remarked. Specifically, we focus our attention: (i) on the construction of Newtonian emission coordinates that are contrasted with those associated with relativistic positioning systems, and (ii) on the role played by non-absolute synchronizations (like the one provided by the local Solar time) in the comprehension of Newtonian and relativistic location systems.

PhysicsTheoretical physicsClassical mechanicsSpace and Planetary ScienceCoordinate systemGeneral EngineeringNewtonian fluidAstronomy and AstrophysicsLocation systemsCausal structureFocus (optics)Realization (systems)Incidence (geometry)EAS Publications Series
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A Real time locating system for local fleet management

2006

Abstract Local locating systems are necessary where a big number of units are handled. In this case, we propose a management system for parking spaces for vehicles that are distributed among eight different-sized lots on a 1.8 million square meter premises. In order to quickly locate each particular vehicle in this area, a new real time location system (RTLS) has been successfully installed. The vehicle location system Moby-R automatically monitors every vehicle movement and tracks its current parked position. All the vehicles are given a data carrier which is attached to the inside rear-view mirror with a special hanger, precisely locating the vehicle within approximately five meters

Real-time locating systemEngineeringVehicle tracking systembusiness.industryPosition (vector)Real-time computingManagement systemLocation systemsbusinessSimulationFleet managementIFAC Proceedings Volumes
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